Life Sciences P1 May June 2025

Confidential
SENIOR CERTIFICATE EXAMINATIONS/
NATIONAL SENIOR CERTIFICATE EXAMINATIONS

LIFE SCIENCES P1

MAY/JUNE 2025

MARKS: 150
TIME: 2½ hours

This question paper consists of 17 pages.

Copyright reserved

INSTRUCTIONS AND INFORMATION

Read the following instructions carefully before answering the questions.

  1. Answer ALL the questions.
  2. Write ALL the answers in the ANSWER BOOK.
  3. Start the answers to EACH question at the top of a NEW page.
  4. Number the answers correctly according to the numbering system used in this question paper.
  5. Present your answers according to the instructions of each question.
  6. Do ALL drawings in pencil and label them in blue or black ink.
  7. Draw diagrams, tables or flow charts only when asked to do so.
  8. The diagrams in this question paper are NOT necessarily drawn to scale.
  9. Do NOT use graph paper.
  10. You must use a non-programmable calculator, protractor and a compass, where necessary.
  11. Write neatly and legibly.
SECTION A

QUESTION 1

1.1
Various options are provided as possible answers to the following questions. Choose the answer and write only the letter (A–D) next to the question numbers (1.1.1 to 1.1.10) in the ANSWER BOOK, e.g. 1.1.11 D.
1.1.1 The part in the amniotic egg that provides nutrients to the developing embryo:
A  Yolk
B  Chorion
C  Amnion
D  Shell
SHOW ANSWER
Correct answer: A — Yolk

The yolk provides nutrients to the developing embryo.

1.1.2 Which gland is responsible for the secretion of prolactin?
A  Thyroid gland
B  Adrenal gland
C  Ovary
D  Pituitary gland
SHOW ANSWER
Correct answer: D — Pituitary gland

The pituitary gland secretes prolactin.

1.1.3 After an accident, a person can still walk, but has poor control and coordination of the skeletal muscles.

The diagram below represents part of the central nervous system of this person.

Part of the central nervous system, labelled K, L and M
The diagram below represents part of the central nervous system.

Which parts of the central nervous system are probably damaged?

A  K, L and M
B  K and L
C  K and M
D  L and M
SHOW ANSWER
Correct answer: C — K and M
1.1.4 The cranial and spinal nerves are part of the ... nervous system.
A  central
B  peripheral
C  sympathetic
D  parasympathetic
SHOW ANSWER
Correct answer: B — peripheral
1.1.5 The following changes occur at puberty:
(i) Growth of facial hair
(ii) Deepening of the voice
(iii) Onset of menstruation
(iv) Oily skin

Which combination of characteristics occurs due to the secretion of testosterone?

A  (i), (ii) and (iii) only
B  (ii) and (iii) only
C  (i), (ii) and (iv) only
D  (i), (ii), (iii) and (iv)
SHOW ANSWER
Correct answer: C — (i), (ii) and (iv) only
1.1.6 A man is fertile if his semen contains a minimum of 20 million sperm per cm3 and at least 75% of the sperm cells are active.

The table below shows the results of a sperm analysis of four semen samples.

Identify the sample that was obtained from an infertile man.

SampleNUMBER OF SPERM IN SAMPLE (million/cm3)INACTIVE SPERM (%)
A2330
B2520
C2225
D2015
SHOW ANSWER
Correct answer: A — Sample A

Sample A is infertile because it has 30% inactive sperm, meaning only 70% of the sperm are active, which is below the stated minimum of 75% active sperm.

1.1.7 Which ONE of the following is a cause of short-sightedness?
A  The eyeball is too short.
B  The lens is unable to become less convex.
C  The lens is opaque.
D  The surface of the eye is uneven.
SHOW ANSWER
Correct answer: B — The lens is unable to become less convex.
1.1.8 A person has a disorder where she is unable to secrete ADH.

It is most likely that …

A  the renal tubules will become more permeable to water.
B  the blood will have a higher volume of water.
C  large volumes of urine will be produced.
D  more water is reabsorbed by the renal tubules.
SHOW ANSWER
Correct answer: C — large volumes of urine will be produced.
1.1.9 Eagles are birds that lay their eggs high up on mountain cliffs and feed their young once they hatch.

The following is a list of reproductive strategies in vertebrates:

(i) Internal fertilisation
(ii) External fertilisation
(iii) Precocial development
(iv) Parental care
(v) Ovipary

Which combination of strategies applies to eagles?

A  (i), (ii) and (iii) only
B  (i), (iv) and (v) only
C  (ii) and (iii) only
D  (ii), (iii) and (iv) only
SHOW ANSWER
Correct answer: B — (i), (iv) and (v) only
1.1.10 The flow diagram below represents a part of the homeostasis of compound X.
Flow diagram for homeostasis of compound X

Which ONE of the following combinations is CORRECT?

XYZ
ACarbon dioxideHypothalamusPituitary gland
BWaterHypothalamusMedulla oblongata
CCarbon dioxideCarotid arteryMedulla oblongata
DWaterCarotid arteryPituitary gland
SHOW ANSWER
Correct answer: C — Carbon dioxide / Carotid artery / Medulla oblongata

(10 x 2) (20)

1.2

Give the correct biological term for EACH of the following descriptions. Write only the term next to the question numbers (1.2.1 to 1.2.8) in the ANSWER BOOK.

1.2.1 The inner lining of the uterus.
SHOW ANSWER
Endometrium
1.2.2 A brain disorder that results in confusion and memory loss.
SHOW ANSWER
Alzheimer's disease
1.2.3 The plant hormone that plays a role in the falling of leaves from trees.
SHOW ANSWER
Abscisic acid
1.2.4 A reproductive strategy where the foetus develops inside the uterus.
SHOW ANSWER
Vivipary
1.2.5 The type of vision in which both eyes are used to see one image.
SHOW ANSWER
Binocular / stereoscopic vision
1.2.6 The part of the brain that joins the left and the right hemispheres of the cerebrum.
SHOW ANSWER
Corpus callosum
1.2.7 The membrane in the amniotic egg that collects nitrogenous waste.
SHOW ANSWER
Allantois
1.2.8 The plant hormone used to control the growth of weeds (8 x 1) (8)
SHOW ANSWER
Auxins
1.3

Indicate whether each of the descriptions in COLUMN I apply to A ONLY, B ONLY, BOTH A AND B or NONE of the items in COLUMN II. Write A only, B only, both A and B or none next to the question numbers (1.3.1 to 1.3.3) in the ANSWER BOOK.

COLUMN ICOLUMN II
1.3.1 A larger number of male and female gametes are producedA: External fertilisation
B: Internal fertilisation
1.3.2 A plant defence mechanismA: Thorns
B: Chemicals
1.3.3 Contributes to the movement of spermA: Mitochondria
B: Tail

(3 x 2) (6)

SHOW ANSWERS

1.3.1 — A only

1.3.2 — Both A and B

1.3.3 — Both A and B

1.4

The diagram below represents a part of the menstrual cycle that occurs in the human ovary.

Diagram representing part of the menstrual cycle in the human ovary
1.4.1 Name the part of the menstrual cycle represented by the diagram. (1)
SHOW ANSWER
Ovarian cycle
1.4.2 Identify structure:
(a) A (1)
(b) B (1)
(c) C (1)
SHOW ANSWER

(a) Graafian follicle

(b) Ovum

(c) Corpus luteum

1.4.3 Name the hormone that:
(a) Controls the development of structure A (1)
(b) Is secreted by structure A (1)
(c) Stimulates the process occurring at structure D (1)
SHOW ANSWER

(a) FSH / Follicle stimulating hormone

(b) Oestrogen

(c) LH / Luteinising hormone

(7)

1.5

The diagram below represents the human eye.

Diagram of the human eye labelled A to H
1.5.1 Identify part:
(a) D (1)
(b) E (1)
SHOW ANSWER

(a) Pupil

(b) Cornea

1.5.2 Give the LETTER of the:
(a) Choroid (1)
(b) Iris (1)
SHOW ANSWER

(a) F

(b) C

1.5.3 Name the TWO different receptors found in part A. (2)
SHOW ANSWER

Rods

Cones

1.5.4 Give only the LETTERS of THREE parts that are involved in accommodation of the eye. (3)
SHOW ANSWER
B, G and H

(9)

TOTAL SECTION A: 50

SECTION B

QUESTION 2

2.1

The diagram below shows the male reproductive system.

Diagram showing the male reproductive system
2.1.1 Identify part:
(a) E (1)
(b) F (1)
(c) C (1)
SHOW ANSWER

(a) Prostate gland

(b) Seminal vesicle

(c) Urethra

2.1.2 Name the type of gametogenesis that occurs in part D. (1)
SHOW ANSWER
Spermatogenesis
2.1.3 Describe the process named in QUESTION 2.1.2. (4)
SHOW ANSWER

Under the influence of testosterone, diploid cells / germinal epithelium in the seminiferous tubules of the testes undergo meiosis, which reduces the chromosome number and forms haploid sperm cells.

2.1.4 Epididymitis is a condition that causes inflammation in the epididymis. This can cause a blockage between the testes and part B.

Explain how this affects the composition of semen. (2)

SHOW ANSWER

Because the epididymis is blocked, sperm are prevented from entering the vas deferens / leaving the testes. As a result, fewer sperm reach the semen, resulting in few sperm / a low sperm count.

(10)

2.2

The diagram below represents human embryonic development.

Diagram representing human embryonic development
2.2.1 Identify:
(a) Cell B (1)
(b) Structure C (1)
SHOW ANSWER

(a) Zygote

(b) Blastocyst / blastula

2.2.2 Explain the difference between cell A and cell B. (3)
SHOW ANSWER

Cell A is haploid / has 23 chromosomes / contains the genetic material of the female, whereas cell B is diploid / has 46 chromosomes / contains the genetic material of both parents. This is because cell A is not fertilised, whereas cell B is formed after fertilisation and is therefore fertilised.

2.2.3 Name the fluid surrounding the embryo. (1)
SHOW ANSWER
Amniotic fluid
2.2.4 State THREE functions of the fluid named in QUESTION 2.2.3. (3)
SHOW ANSWER
  • Allows for free movement of the foetus.
  • Protects the foetus against mechanical injury / acts as a shock absorber.
  • Prevents dehydration of the foetus.
  • Prevents temperature changes.

(9)

2.3

Basal body temperature is the body temperature while a person is at rest. An increase above the basal body temperature occurs immediately after the day of ovulation. The basal body temperature method can be used by women who want to fall pregnant.

The graph below represents the body temperature chart of a woman with a 28-day menstrual cycle.

Body temperature chart of a woman with a 28-day menstrual cycle
2.3.1 Use the graph to identify the following for this woman:
(a) Basal body temperature (1)
(b) Day of ovulation (1)
SHOW ANSWER

(a) 36,2˚C

(b) Day 16

2.3.2 Using evidence in the graph, give a reason for your answer to QUESTION 2.3.1(b). (2)
SHOW ANSWER
Body temperature increased above basal body temperature / 36.2˚C immediately after day 16.
2.3.3 Progesterone is the hormone that causes an increase in the basal body temperature.

Explain why the increase in basal body temperature occurs only after ovulation. (2)

SHOW ANSWER

The increase in basal body temperature occurs only after ovulation because the corpus luteum is formed after ovulation and it secretes progesterone. The secretion of progesterone therefore causes the basal body temperature to increase after ovulation.

2.3.4 Explain why the basal body temperature is measured when a person is at rest. (2)
SHOW ANSWER

Basal body temperature is measured when a person is at rest because physical activity / increased cellular respiration changes body temperature. By measuring the temperature at rest, low physical activity / cellular respiration prevents a change in body temperature from affecting the reading.

(8)

2.4

Read the extract below.

HEARING LOSS

There are two main types of hearing loss. Type A hearing loss occurs when there is a blockage in the transmission of sound waves and vibrations through the outer and middle ear. Type B hearing loss is caused by damage to the hearing receptors of the inner ear or to the nerves that carry sound impulses to the brain.

The diagram below represents the human ear.

Diagram of the human ear labelled P, Q, R, S and T
2.4.1 Write down only the LETTERS of TWO parts EACH that may be damaged when a person suffers from:
(a) Type A hearing loss (2)
(b) Type B hearing loss (2)
SHOW ANSWER

(a) P and T

(b) S and R

2.4.2 Identify part S. (1)
SHOW ANSWER
Cochlea
2.4.3 Describe the role of the hearing receptors when they are stimulated by pressure waves. (2)
SHOW ANSWER

When the hearing receptors are stimulated by pressure waves, they convert the stimulus / pressure waves to an impulse and then transfer it to the auditory nerve.

2.4.4 Explain why a person will suffer from hearing loss if the bones at P are fused. (4)
SHOW ANSWER

If the bones at P are fused, the ossicles will not vibrate freely / fewer or no vibrations will be carried to the oval window. This causes decreased amplification of sound, so fewer or no pressure waves will form in the cochlea. As a result, the receptors in the cochlea will not be stimulated / will be stimulated less, and therefore less or no impulses will reach the cerebrum.

(11)

2.5

Scientists investigated the effect of different doses of alcohol on reaction time in humans.

  • A dose is the amount of alcohol given per kilogram of body mass.
  • Reaction time is the time it takes a person to react once a stimulus is received.

The procedure was as follows:

  • Two 30-year-old male volunteers participated in the investigation which was conducted for a period of 7 days.
  • They did not drink alcohol for a period of 24 hours prior to testing.
  • They were given different amounts of alcohol on 4 different days.
  • Their reaction times were determined 30 minutes after consuming the alcohol.

The results of the investigation are shown in the table below.

DAY OF INVESTIGATIONALCOHOL DOSE (mg/kg body mass)REACTION TIME (seconds) — MALE 1REACTION TIME (seconds) — MALE 2
101,861,82
32001,911,94
54002,022,06
76002,112,15
2.5.1 For this investigation, state the:
(a) Independent variable (1)
(b) Dependent variable (1)
SHOW ANSWER

(a) Alcohol dose

(b) Reaction time

2.5.2 Name TWO variables that were controlled during the investigation. (2)
SHOW ANSWER
  • Age / 30 years old.
  • Gender / men.
  • Volunteers were tested over a period of 7 days.
  • Volunteers abstained from alcohol for 24 hours prior to testing.
  • Volunteers had their reaction time measured 30 minutes after consuming the alcohol / period from consumption to testing was the same.
2.5.3 State TWO ways in which the reliability of the results can be improved. (2)
SHOW ANSWER
  • Use more than 2 volunteers / increase the number of volunteers.
  • Repeat the investigation / take multiple readings for the same dose.
2.5.4 Explain why the participants only received alcohol every second day. (2)
SHOW ANSWER

The participants only received alcohol every second day to ensure that there is no alcohol in the body from the previous dose and that only the alcohol given on the day is tested for.

2.5.5 Male 1 has a body mass of 93 kg. Calculate the amount of alcohol (in mg) that he consumed on day 7 of the investigation. Show ALL your working. (2)
SHOW ANSWER
(93 × 600) = 55 800 mg
2.5.6 State a conclusion for this investigation. (2)
SHOW ANSWER

The results show that higher doses of alcohol increase the reaction time, as the reaction time increased as the alcohol dose increased.

(12)

[50]

QUESTION 3

3.1

The diagram below represents part of a reflex arc.

Diagram representing part of a reflex arc
3.1.1 Give the LETTER of the part that represents the:
(a) Dorsal root (1)
(b) Sensory neuron (1)
SHOW ANSWER

(a) B

(b) A

3.1.2 State the significance of a synapse. (1)
SHOW ANSWER

A synapse ensures that nerve impulses are transmitted in one direction, from one neuron to the next.

3.1.3 Explain the:
(a) Significance of a reflex action (2)
(b) Effect on the reflex arc if neuron A is cut (3)
SHOW ANSWER

(a) A reflex action is a rapid / automatic reaction to a stimulus that protects the body from damage. Because the response occurs rapidly and automatically, the body can react quickly to a potentially harmful stimulus.

(b) If neuron A is cut, no impulse will be transmitted from the receptor to the spinal cord / interneuron. As a result, the effector will not be stimulated.

3.1.4 Draw a labelled diagram to show the detailed structure of neuron D. (5)
SHOW ANSWER

Model answer: Diagram of a motor neuron (D), with a correct caption and any three correct labels.

Model answer: diagram of a motor neuron

(13)

3.2

Read the extract below.

INSULIN PUMPS

In people with diabetes mellitus, the beta cells in the pancreas are unable to secrete sufficient amounts of insulin. These people are treated with regular injections of insulin.

Electronic pumps have been developed as an alternative to injections. They pump insulin into the blood according to different blood glucose concentrations. The pump can be clipped to a piece of clothing or fastened to the skin with an adhesive patch. These pumps then infuse insulin through the skin into the blood.

3.2.1 Identify the:
(a) Groups of cells in the pancreas that contain the beta cells (1)
(b) Signal for the pump to turn on and start pumping insulin (1)
SHOW ANSWER

(a) Islets of Langerhans

(b) A high concentration of glucose in the blood

3.2.2 State why the cells identified in QUESTION 3.2.1(a) have endocrine characteristics. (2)
SHOW ANSWER

The cells have endocrine characteristics because they secrete hormones / insulin / glucagon directly into the blood and have no ducts through which the hormones are released.

3.2.3 Describe the effect of insulin on the liver and the muscles. (2)
SHOW ANSWER

Insulin stimulates the conversion of glucose to glycogen in the liver and promotes the absorption / usage of glucose by the muscle cells. This helps to reduce the concentration of glucose in the blood.

3.2.4 Explain why electronic pumps are more effective in controlling blood glucose levels than insulin injections. (2)
SHOW ANSWER

Electronic pumps are more effective because they deliver insulin specifically according to the glucose level, allowing for better blood glucose management / regular dosing. In this way, insulin delivery can respond to changes in blood glucose levels.

(8)

3.3

Describe the role of the human skin in the regulation of body temperature on a cold day. (6)

SHOW ANSWER

Cold receptors in the skin convert the stimulus to an impulse which is sent to the hypothalamus. The hypothalamus stimulates vasoconstriction in the skin / stimulates blood vessels of the skin to constrict. Less blood flows to the skin / sweat glands, so less heat is lost from the skin through radiation. The sweat glands are stimulated to produce less sweat and less heat is lost through evaporation of sweat.

3.4

Knowing the salt level in the blood of humans can provide information on their health and lifestyle. The normal salt level in the blood is between 136 mmol/ℓ and 145 mmol/ℓ. Salt levels in the blood below 136 mmol/ℓ are an indication of hyponatremia, and salt levels in the blood higher than 145 mmol/ℓ are an indication of hypernatremia.

A group of people with the same diet had their blood salt levels tested.

The table below shows the results.

SALT LEVELS IN THE BLOOD (mmol/ℓ)NUMBER OF PEOPLE
Lower than 1365
136 to 14015
141 to 14521
Higher than 1454
3.4.1 Use data in the table to determine how many people have:
(a) Hypernatremia (1)
(b) Normal blood salt levels (1)
SHOW ANSWER

(a) 4

(b) 36

3.4.2 Describe how the human body increases a salt level lower than 136 mmol/ℓ to the normal level. (6)
SHOW ANSWER

Receptor cells detect the low salt level, after which the adrenal glands are stimulated and more aldosterone is secreted. The increased aldosterone causes the reabsorption of salt / sodium in the renal tubules into the surrounding blood capillaries to increase. As a result, less salt is excreted, causing the salt level in the blood to increase towards the normal level.

3.4.3 Draw a histogram to show the results in the table. (6)
SHOW ANSWER

Model histogram:

Model histogram showing number of people with different salt levels in the blood

Graph requirements: use a histogram; include a caption containing both variables; label the X- and Y-axes correctly, including the correct unit for the X-axis; use the correct scale; use equal-width bars with no spaces; plot all four coordinates correctly.

(14)

3.5

An investigation was conducted to determine the response of plant seedlings to light.

The procedure was as follows:

  • Grain seeds were allowed to germinate into seedlings.
  • One half of the seedlings were planted in one small pot and the other half in another small pot.
  • When the stems reached a height of approximately 1 cm, the pots were placed on the discs of two clinostats. A clinostat is an apparatus consisting of a slowly rotating disc when switched on.
  • Both sets of apparatus (A and B) were placed inside boxes with openings on one side only for light to enter (unilateral light).
  • One clinostat was switched on and the other one was switched off.
  • The apparatus was left for two weeks.

The results after two weeks are represented in the diagram below.

Results after two weeks for the plant seedling clinostat investigation
3.5.1 Identify the plant growth response demonstrated by the results. (1)
SHOW ANSWER
Phototropism
3.5.2 In which apparatus (A or B) was the clinostat switched on and the disc rotating slowly? (1)
SHOW ANSWER
B
3.5.3 Explain your answer to QUESTION 3.5.2. (2)
SHOW ANSWER

All the seedlings grew straight up / showed no phototropism because they were evenly exposed to light / not exposed to unilateral light. As a result, there was equal distribution of auxins, so no side of the seedlings experienced greater growth than the other.

3.5.4 Explain the growth response of the seedlings in apparatus A. (5)
SHOW ANSWER

The seedlings/stems grew/bent to the left / towards the light because they were exposed to light from one side / unilateral light. In response to the unilateral light, auxins diffuse to the right / dark side of the seedlings, where their concentration becomes higher. The high concentration of auxins on the right / dark side stimulates cell elongation / cell division / growth on that side. As the cells on the right side grow more, that side becomes longer and the seedlings/stems bend towards the light.

(9)

[50]

TOTAL SECTION B: 100

GRAND TOTAL: 150

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